Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.S100Y

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.S100Y
c.299C>A
Surrounding Variants
1 paper
NM_002582.4
p.S100F
c.299C>T
1 paper
NM_002582.4
p.S100S
c.300C>A
1 paper
NM_002582.4
p.S101P
c.301T>C
1 paper
NM_002582.4
p.R99T
c.296G>C
1 paper
NM_002582.4
p.P102L
c.305C>T
1 paper
NM_002582.4
p.N98S
c.293A>G
1 paper
NM_002582.4
p.N98D
c.292A>G
3 papers
NM_002582.4
p.P94_P102delFs
c.281_306del26
1 paper
NM_002582.4
p.V104G
c.311T>G
1 paper
NM_002582.4
p.V104A
c.311T>C
1 paper
NM_002582.4
p.P96L
c.287C>T
1 paper
NM_002582.4
p.P96A
c.286C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."