Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.F67S

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.F67S
c.200T>C
Surrounding Variants
1 paper
NM_002582.4
p.F67L
c.201T>G
1 paper
NM_002582.4
p.F67L
c.199T>C
1 paper
NM_002582.4
p.F67L
c.201T>A
1 paper
NM_002582.4
p.Q68L
c.203A>T
1 paper
NM_002582.4
p.Q68P
c.203A>C
5 papers
NM_002582.4
p.Q68H
c.204G>T
5 papers
NM_002582.4
p.Q68H
c.204G>C
1 paper
NM_002582.4
p.L65F
c.195G>T
1 paper
NM_002582.4
p.L65F
c.195G>C
1 paper
NM_002582.4
p.L65delFs
c.194delA
1 paper
NM_002582.4
p.F69C
c.206T>G
1 paper
NM_002582.4
p.L65fs
c.193_194fs
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