Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.D63G

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.D63G
c.188A>G
Surrounding Variants
1 paper
NM_002582.4
p.D63A
c.188A>C
1 paper
NM_002582.4
p.D63H
c.187G>C
1 paper
NM_002582.4
p.D63E
c.189C>G
1 paper
NM_002582.4
p.D63E
c.189C>A
1 paper
NM_002582.4
p.F64L
c.190T>C
1 paper
NM_002582.4
p.F64L
c.192T>G
1 paper
NM_002582.4
p.F64L
c.192T>A
1 paper
NM_002582.4
p.M62V
c.184A>G
1 paper
NM_002582.4
p.L65fs
c.193_194fs
3 papers
NM_002582.4
p.S61C
c.182C>G
1 paper
NM_002582.4
p.L65F
c.195G>T
1 paper
NM_002582.4
p.L65F
c.195G>C
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."