Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.F31L

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.F31L
c.93T>G
Surrounding Variants
1 paper
NM_002582.4
p.F31L
c.93T>A
1 paper
NM_002582.4
p.F25_F31delFs
c.75_93del19
1 paper
NM_002582.4
p.S32fs
c.94_95fs
1 paper
NM_002582.4
p.F31L
c.91T>C
1 paper
NM_002582.4
p.S32L
c.95C>T
1 paper
NM_002582.4
p.S32delFs
c.94delA
1 paper
NM_002582.4
p.G33*
c.97G>T
1 paper
NM_002582.4
p.E30G
c.89A>G
2 papers
NM_002582.4
p.E30A
c.89A>C
1 paper
NM_002582.4
p.E30insFs
c.88dupG
1 paper
NM_002582.4
p.G33Splc
c.97+1G>A
1 paper
NM_002582.4
p.E30K
c.88G>A
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