Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.E21G

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.E21G
c.62A>G
Surrounding Variants
1 paper
NM_002582.4
p.E21*
c.61G>T
1 paper
NM_002582.4
p.E21K
c.61G>A
1 paper
NM_002582.4
p.D23Y
c.67G>T
1 paper
NM_002582.4
p.D23N
c.67G>A
1 paper
NM_002582.4
p.I19M
c.57A>G
1 paper
NM_002582.4
p.I19T
c.56T>C
2 papers
NM_002582.4
p.I19V
c.55A>G
1 paper
NM_002582.4
p.F24L
c.70T>C
1 paper
NM_002582.4
p.F24S
c.71T>C
1 paper
NM_002582.4
p.F24Y
c.71T>A
1 paper
NM_002582.4
p.A18V
c.53C>T
1 paper
NM_002582.4
p.V15_Q17del3
c.43_50del9
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."