Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.Q17K

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.Q17K
c.49C>A
Surrounding Variants
1 paper
NM_002582.4
p.Q17L
c.50A>T
1 paper
NM_002582.4
p.Q17R
c.50A>G
1 paper
NM_002582.4
p.Y16C
c.47A>G
2 papers
NM_002582.4
p.Y16S
c.47A>C
1 paper
NM_002582.4
p.A18V
c.53C>T
1 paper
NM_002582.4
p.V15_Q17del3
c.43_50del9
1 paper
NM_002582.4
p.V15A
c.44T>C
1 paper
NM_002582.4
p.V15L
c.43G>T
1 paper
NM_002582.4
p.V15L
c.43G>C
1 paper
NM_002582.4
p.V15M
c.43G>A
2 papers
NM_002582.4
p.I19V
c.55A>G
1 paper
NM_002582.4
p.I19T
c.56T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."