Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.Y16C

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.Y16C
c.47A>G
Surrounding Variants
2 papers
NM_002582.4
p.Y16S
c.47A>C
1 paper
NM_002582.4
p.Q17K
c.49C>A
1 paper
NM_002582.4
p.V15A
c.44T>C
1 paper
NM_002582.4
p.Q17L
c.50A>T
1 paper
NM_002582.4
p.Q17R
c.50A>G
1 paper
NM_002582.4
p.V15L
c.43G>T
1 paper
NM_002582.4
p.V15L
c.43G>C
1 paper
NM_002582.4
p.V15M
c.43G>A
1 paper
NM_002582.4
p.K14N
c.42A>T
1 paper
NM_002582.4
p.K14K
c.42A>G
1 paper
NM_002582.4
p.K14N
c.42A>C
1 paper
NM_002582.4
p.A18V
c.53C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."