Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.N11D

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.N11D
c.31A>G
Surrounding Variants
1 paper
NM_002582.4
p.N11S
c.32A>G
1 paper
NM_002582.4
p.N11T
c.32A>C
1 paper
NM_002582.4
p.N11K
c.33T>G
1 paper
NM_002582.4
p.N11K
c.33T>A
1 paper
NM_002582.4
p.S10T
c.29G>C
1 paper
NM_002582.4
p.S10N
c.29G>A
2 papers
NM_002582.4
p.L12F
c.34C>T
1 paper
NM_002582.4
p.L12V
c.34C>G
1 paper
NM_002582.4
p.K9M
c.26A>T
1 paper
NM_002582.4
p.F8_K9del1
c.23_25delTAA
1 paper
NM_002582.4
p.H13Y
c.37C>T
1 paper
NM_002582.4
p.H13N
c.37C>A
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