Varaico: Literature-Extracted Genetic Variants

PARP10

65 papers

RefSeq Summary

Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofact...

Pfam Domains

RRM_PARP14_3aa 11–83UCSCPARP14, third RRM domain

RRM_PARP14_3aa 172–253UCSCPARP14, third RRM domain

KH_PARP10aa 731–790UCSCProtein mono-ADP-ribosyltransferase PARP10, KH-domain type I

PARPaa 827–957UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase family member 10

HGNC Alias Symbols

FLJ14464; ARTD10

Papers

RefSeq ID

Protein change

DNA change

1–12 of 99 variants

4 papers

NM_032789.5

p.V630A

c.1889T>C

3 papers

NM_032789.5

p.L395P

c.1184T>C

2 papers

NM_032789.5

p.P102A

c.304C>G

2 papers

NM_032789.5

p.I249V

c.745A>G

1 paper

NM_032789.5

p.A5V

c.14C>T

1 paper

NM_032789.5

p.V11G

c.32T>G

1 paper

NM_032789.5

p.A12T

c.34G>A

1 paper

NM_032789.5

p.F31S

c.92T>C

1 paper

NM_032789.5

p.S37C

c.110C>G

1 paper

NM_032789.5

p.G49fs

c.145_146fs

1 paper

NM_032789.5

p.G49delFs

c.146delC

1 paper

NM_032789.5

p.G51W

c.151G>T