Varaico: Literature-Extracted Genetic Variants

PARP10

65 papers

RefSeq Summary

Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofact...

Pfam Domains

RRM_PARP14_3aa 11–83UCSCPARP14, third RRM domain

RRM_PARP14_3aa 172–253UCSCPARP14, third RRM domain

KH_PARP10aa 731–790UCSCProtein mono-ADP-ribosyltransferase PARP10, KH-domain type I

PARPaa 827–957UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase family member 10

HGNC Alias Symbols

FLJ14464; ARTD10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_032789.5

p.V630A

c.1889T>C

Surrounding Variants

1 paper

NM_032789.5

p.E628K

c.1882G>A

1 paper

NM_032789.5

p.E636K

c.1906G>A

1 paper

NM_032789.5

p.E637K

c.1909G>A

1 paper

NM_032789.5

p.E619Q

c.1855G>C

1 paper

NM_032789.5

p.E610G

c.1829A>G

1 paper

NM_032789.5

p.A671delFs

c.2011delC

1 paper

NM_032789.5

p.A671fs

c.2011_2012fs

1 paper

NM_032789.5

p.A682S

c.2044G>T

1 paper

NM_032789.5

p.P699fs

c.2095_2096fs

1 paper

NM_032789.5

p.P699delFs

c.2096delG

1 paper

NM_032789.5

p.R724W

c.2170C>T

1 paper

NM_032789.5

p.V590M

c.1768G>A