Varaico: Literature-Extracted Genetic Variants

PARP10

65 papers

RefSeq Summary

Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofact...

Pfam Domains

RRM_PARP14_3aa 11–83UCSCPARP14, third RRM domain

RRM_PARP14_3aa 172–253UCSCPARP14, third RRM domain

KH_PARP10aa 731–790UCSCProtein mono-ADP-ribosyltransferase PARP10, KH-domain type I

PARPaa 827–957UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase family member 10

HGNC Alias Symbols

FLJ14464; ARTD10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_032789.5

p.I249V

c.745A>G

Surrounding Variants

1 paper

NM_032789.5

p.T216fs

c.646_647fs

1 paper

NM_032789.5

p.G202E

c.605G>A

1 paper

NM_032789.5

p.P328A

c.982C>G

1 paper

NM_032789.5

p.S334F

c.1001C>T

1 paper

NM_032789.5

p.P339delFs

c.1017delG

1 paper

NM_032789.5

p.M340I

c.1020G>A

1 paper

NM_032789.5

p.V184L

c.550G>T

1 paper

NM_032789.5

p.V184L

c.550G>C

1 paper

NM_032789.5

p.D180fs

c.538_539fs

1 paper

NM_032789.5

p.D180delFs

c.538delC

1 paper

NM_032789.5

p.A346V

c.1037C>T

1 paper

NM_032789.5

p.R176delFs

c.527delC