Varaico: Literature-Extracted Genetic Variants

PARP14

103 papers

RefSeq Summary

This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased ...

Pfam Domains

RRM_PARP14_1aa 9–88UCSCPAR14-like, first RRM domain

RRM_PARP14_2aa 146–225UCSCPARP14, second RRM domain

RRM_PARP14_3aa 227–308UCSCPARP14, third RRM domain

KH_PARP14_1aa 314–394UCSCPARP14, first type I KH domain

KH_PARP14_2aa 398–466UCSCPARP14, second type I KH domain

KH_PARP14_3aa 471–531UCSCPARP14, third type I KH domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase family member 14

HGNC Alias Symbols

KIAA1268; pART8; ARTD8; BAL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_017554.3

p.T631A

c.1891A>G

Surrounding Variants

1 paper

NM_017554.3

p.L617L

c.1851C>G

1 paper

NM_017554.3

p.E587insFs

c.1759_1760ins8

1 paper

NM_017554.3

p.E587fs

c.1759_1760fs

2 papers

NM_017554.3

p.A561E

c.1682C>A

1 paper

NM_017554.3

p.A561T

c.1681G>A

1 paper

NM_017554.3

p.Q712K

c.2134C>A

1 paper

NM_017554.3

p.T722I

c.2165C>T

1 paper

NM_017554.3

p.A750T

c.2248G>A

1 paper

NM_017554.3

p.D502N

c.1504G>A

1 paper

NM_017554.3

p.E498A

c.1493A>C

1 paper

NM_017554.3

p.I765I

c.2295C>A

1 paper

NM_017554.3

p.R450K

c.1349G>A