Varaico: Literature-Extracted Genetic Variants

PARP14

103 papers

RefSeq Summary

This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased ...

Pfam Domains

RRM_PARP14_1aa 9–88UCSCPAR14-like, first RRM domain

RRM_PARP14_2aa 146–225UCSCPARP14, second RRM domain

RRM_PARP14_3aa 227–308UCSCPARP14, third RRM domain

KH_PARP14_1aa 314–394UCSCPARP14, first type I KH domain

KH_PARP14_2aa 398–466UCSCPARP14, second type I KH domain

KH_PARP14_3aa 471–531UCSCPARP14, third type I KH domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase family member 14

HGNC Alias Symbols

KIAA1268; pART8; ARTD8; BAL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017554.3

p.T1437M

c.4310C>T

Surrounding Variants

1 paper

NM_017554.3

p.W1445*

c.4334G>A

1 paper

NM_017554.3

p.W1445*

c.4335G>A

1 paper

NM_017554.3

p.D1448delFs

c.4344delC

1 paper

NM_017554.3

p.I1484V

c.4450A>G

1 paper

NM_017554.3

p.S1403A

c.4207T>G

1 paper

NM_017554.3

p.A1507D

c.4520C>A

1 paper

NM_017554.3

p.E1525K

c.4573G>A

1 paper

NM_017554.3

p.E1525D

c.4575A>C

1 paper

NM_017554.3

p.E1525D

c.4575A>T

1 paper

NM_017554.3

p.D1541E

c.4623C>A

1 paper

NM_017554.3

p.D1541E

c.4623C>G

1 paper

NM_017554.3

p.A1350V

c.4049C>T