Varaico: Literature-Extracted Genetic Variants

PARP2

131 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain whi...

Pfam Domains

WGRaa 115–195UCSCWGR domain

PARP_regaa 232–362UCSCPoly(ADP-ribose) polymerase, regulatory domain

PARPaa 376–577UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase 2

HGNC Previous Symbol

ADPRTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001042618.2

p.K37Q

c.109A>C

Surrounding Variants

3 papers

NM_001042618.2

p.K37R

c.110A>G

1 paper

NM_001042618.2

p.A36V

c.107C>T

1 paper

NM_001042618.2

p.R40C

c.118C>T

1 paper

NM_001042618.2

p.R40H

c.119G>A

1 paper

NM_001042618.2

p.N27N

c.81C>T

2 papers

NM_001042618.2

p.N24fs

c.70_71fs

1 paper

NM_001042618.2

p.N24Y

c.70A>T

1 paper

NM_001042618.2

p.N24delFs

c.71_72delAT

1 paper

NM_001042618.2

p.P51A

c.151C>G

1 paper

NM_001042618.2

p.R22I

c.65G>T

1 paper

NM_001042618.2

p.D64H

c.190G>C

1 paper

NM_001042618.2

p.V70L

c.208G>C