Varaico: Literature-Extracted Genetic Variants

PARP2

131 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain whi...

Pfam Domains

WGRaa 115–195UCSCWGR domain

PARP_regaa 232–362UCSCPoly(ADP-ribose) polymerase, regulatory domain

PARPaa 376–577UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase 2

HGNC Previous Symbol

ADPRTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001042618.2

p.L285P

c.854T>C

Surrounding Variants

1 paper

NM_001042618.2

p.R283Q

c.848G>A

1 paper

NM_001042618.2

p.R283*

c.847C>T

1 paper

NM_001042618.2

p.H281Q

c.843T>A

1 paper

NM_005484.4

p.E304Q

c.910G>C

1 paper

NM_001042618.2

p.R277W

c.829C>T

1 paper

NM_001042618.2

p.Q267*

c.799C>T

1 paper

NM_001042618.2

p.A252T

c.754G>A

1 paper

NM_001042618.2

p.I232fs

c.694_695fs

1 paper

NM_001042618.2

p.D222G

c.665A>G

1 paper

NM_001042618.2

p.K207insFs

c.619_620insG

1 paper

NM_001042618.2

p.K206insFs

c.617_618insG

1 paper

NM_001042618.2

p.E204fs

c.610_611fs