Varaico: Literature-Extracted Genetic Variants

PARP2

131 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain whi...

Pfam Domains

WGRaa 115–195UCSCWGR domain

PARP_regaa 232–362UCSCPoly(ADP-ribose) polymerase, regulatory domain

PARPaa 376–577UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase 2

HGNC Previous Symbol

ADPRTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001042618.2

p.I331insFs

c.991_992insA

Surrounding Variants

2 papers

NM_001042618.2

p.I329insFs

c.985_986insA

1 paper

NM_001042618.2

p.I327insFs

c.979_980insTT

1 paper

NM_005484.4

p.L358V

c.1072T>G

1 paper

NM_001042618.2

p.N351H

c.1051A>C

1 paper

NM_001042618.2

p.P358L

c.1073C>T

1 paper

NM_001042618.2

p.R309W

c.925C>T

1 paper

NM_001042618.2

p.T304S

c.911C>G

1 paper

NM_001042618.2

p.T304S

c.910A>T

2 papers

NM_001042618.2

p.S370insFs

c.1109_1110insT

1 paper

NM_001042618.2

p.H377H

c.1131T>C

1 paper

NM_001042618.2

p.D383N

c.1147G>A

1 paper

NM_001042618.2

p.L412L

c.1236T>C