Varaico: Literature-Extracted Genetic Variants

PARP2

131 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain whi...

Pfam Domains

WGRaa 115–195UCSCWGR domain

PARP_regaa 232–362UCSCPoly(ADP-ribose) polymerase, regulatory domain

PARPaa 376–577UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase 2

HGNC Previous Symbol

ADPRTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001042618.2

p.W422C

c.1266G>C

Surrounding Variants

1 paper

NM_001042618.2

p.W422C

c.1266G>T

1 paper

NM_001042618.2

p.I425S

c.1274T>G

1 paper

NM_001042618.2

p.H428Y

c.1282C>T

1 paper

NM_001042618.2

p.H415Y

c.1243C>T

1 paper

NM_001042618.2

p.L412L

c.1236T>C

1 paper

NM_001042618.2

p.D383N

c.1147G>A

1 paper

NM_001042618.2

p.H377H

c.1131T>C

2 papers

NM_001042618.2

p.S370insFs

c.1109_1110insT

1 paper

NM_001042618.2

p.M453I

c.1359G>A

1 paper

NM_001042618.2

p.K456E

c.1366A>G

1 paper

NM_001042618.2

p.N459S

c.1376A>G

1 paper

NM_001042618.2

p.Y460Y

c.1380C>T