Varaico: Literature-Extracted Genetic Variants

PARP4

244 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly...

Pfam Domains

BRCTaa 1–81UCSCBRCA1 C Terminus (BRCT) domain

WGR-like_PARP4aa 144–257UCSCPARP4 WGR-like domain

PARPaa 389–566UCSCPoly(ADP-ribose) polymerase catalytic domain

VITaa 623–733UCSCVault protein inter-alpha-trypsin domain

VWAaa 876–1042UCSCvon Willebrand factor type A domain

PARP4_MVP-IDaa 1575–1721UCSCPARP4 MVP-ID C-terminal domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase family member 4

HGNC Previous Symbol

ADPRTL1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 243 variants

20 papers

NM_006437.4

p.I1039T

c.3116T>C

18 papers

NM_006437.4

p.T1170I

c.3509C>T

15 papers

NM_006437.4

p.Q1059R

c.3176A>G

14 papers

NM_006437.4

p.V458I

c.1372G>A

11 papers

NM_006437.4

p.A899T

c.2695G>A

11 papers

NM_006437.4

p.G1280R

c.3838G>C

10 papers

NM_006437.4

p.V1065A

c.3194T>C

7 papers

NM_006437.4

p.G496V

c.1487G>T

7 papers

NM_006437.4

p.G1265A

c.3794G>C

7 papers

NM_006437.4

p.P1328T

c.3982C>A

6 papers

NM_006437.4

p.H490Q

c.1470C>G

6 papers

NM_006437.4

p.H490Q

c.1470C>A