Varaico: Literature-Extracted Genetic Variants

PARP4

244 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly...

Pfam Domains

BRCTaa 1–81UCSCBRCA1 C Terminus (BRCT) domain

WGR-like_PARP4aa 144–257UCSCPARP4 WGR-like domain

PARPaa 389–566UCSCPoly(ADP-ribose) polymerase catalytic domain

VITaa 623–733UCSCVault protein inter-alpha-trypsin domain

VWAaa 876–1042UCSCvon Willebrand factor type A domain

PARP4_MVP-IDaa 1575–1721UCSCPARP4 MVP-ID C-terminal domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase family member 4

HGNC Previous Symbol

ADPRTL1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006437.4

p.H1455R

c.4364A>G

Surrounding Variants

2 papers

NM_006437.4

p.S1459Y

c.4376C>A

1 paper

NM_006437.4

p.H1438R

c.4313A>G

1 paper

NM_006437.4

p.N1474I

c.4421A>T

1 paper

NM_006437.4

p.P1435S

c.4303C>T

1 paper

NM_006437.4

p.S1407R

c.4221C>G

1 paper

NM_006437.4

p.S1407R

c.4221C>A

1 paper

NM_006437.4

p.S1407R

c.4219A>C

2 papers

NM_006437.4

p.S1394A

c.4180T>G

1 paper

NM_006437.4

p.Q1389*

c.4165C>T

1 paper

NM_006437.4

p.T1385I

c.4154C>T

1 paper

NM_006437.4

p.D1547G

c.4640A>G

1 paper

NM_006437.4

p.S1362F

c.4085C>T