Varaico: Literature-Extracted Genetic Variants

PARP4

244 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly...

Pfam Domains

BRCTaa 1–81UCSCBRCA1 C Terminus (BRCT) domain

WGR-like_PARP4aa 144–257UCSCPARP4 WGR-like domain

PARPaa 389–566UCSCPoly(ADP-ribose) polymerase catalytic domain

VITaa 623–733UCSCVault protein inter-alpha-trypsin domain

VWAaa 876–1042UCSCvon Willebrand factor type A domain

PARP4_MVP-IDaa 1575–1721UCSCPARP4 MVP-ID C-terminal domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase family member 4

HGNC Previous Symbol

ADPRTL1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006437.4

p.R1332C

c.3994C>T

Surrounding Variants

1 paper

NM_006437.4

p.R1332R

c.3996C>T

1 paper

NM_006437.4

p.A1331T

c.3991G>A

1 paper

NM_006437.4

p.P1329P

c.3987G>A

1 paper

NM_006437.4

p.P1329L

c.3986C>T

2 papers

NM_006437.4

p.P1328S

c.3982C>T

7 papers

NM_006437.4

p.P1328T

c.3982C>A

1 paper

NM_006437.4

p.F1316insFs

c.3948dupT

1 paper

NM_006437.4

p.S1313C

c.3938C>G

1 paper

NM_006437.4

p.S1362F

c.4085C>T

1 paper

NM_006437.4

p.S1292T

c.3874T>A

1 paper

NM_006437.4

p.G1280C

c.3838G>T

11 papers

NM_006437.4

p.G1280R

c.3838G>C