Varaico: Literature-Extracted Genetic Variants

PARP4

244 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly...

Pfam Domains

BRCTaa 1–81UCSCBRCA1 C Terminus (BRCT) domain

WGR-like_PARP4aa 144–257UCSCPARP4 WGR-like domain

PARPaa 389–566UCSCPoly(ADP-ribose) polymerase catalytic domain

VITaa 623–733UCSCVault protein inter-alpha-trypsin domain

VWAaa 876–1042UCSCvon Willebrand factor type A domain

PARP4_MVP-IDaa 1575–1721UCSCPARP4 MVP-ID C-terminal domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase family member 4

HGNC Previous Symbol

ADPRTL1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006437.4

p.N444I

c.1331A>T

Surrounding Variants

1 paper

NM_006437.4

p.K429E

c.1285A>G

1 paper

NM_006437.4

p.F426S

c.1277T>C

14 papers

NM_006437.4

p.V458I

c.1372G>A

1 paper

NM_006437.4

p.V459A

c.1376T>C

2 papers

NM_006437.4

p.G470R

c.1408G>C

2 papers

NM_006437.4

p.G470R

c.1408G>A

1 paper

NM_006437.4

p.L472V

c.1414C>G

1 paper

NM_006437.4

p.G475E

c.1424G>A

1 paper

NM_006437.4

p.S481L

c.1442C>T

1 paper

NM_006437.4

p.L482F

c.1444C>T

1 paper

NM_006437.4

p.H404Y

c.1210C>T

1 paper

NM_006437.4

p.E398K

c.1192G>A