Varaico: Literature-Extracted Genetic Variants

Gene:PCNA
Variant:p.K117E

PCNA

2,862 papers

RefSeq Summary

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synth...

Pfam Domains

PCNA_Naa 1–125UCSCProliferating cell nuclear antigen, N-terminal domain
PCNA_Caa 127–254UCSCProliferating cell nuclear antigen, C-terminal domain

Gene Aliases

HGNC Name

proliferating cell nuclear antigen

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_182649.2
p.K117E
c.349A>G
Surrounding Variants
7 papers
NM_182649.2
p.K117R
c.350A>G
1 paper
NM_182649.2
p.E115delFs
c.344delT
2 papers
NM_182649.2
p.K117N
c.351G>T
2 papers
NM_182649.2
p.K117N
c.351G>C
1 paper
NM_182649.2
p.E115E
c.345A>G
1 paper
NM_182649.2
p.L118L
c.354G>A
1 paper
NM_182649.2
p.E115V
c.344A>T
1 paper
NM_182649.2
p.E115_M116insT
c.343_347ins3
2 papers
NM_182649.2
p.M119T
c.356T>C
1 paper
NM_182649.2
p.M119K
c.356T>A
1 paper
NM_182649.2
p.M119delFs
c.356delA
3 papers
NM_182649.2
p.Y114F
c.341A>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."