Varaico: Literature-Extracted Genetic Variants

Gene:PCNA
Variant:p.S74Splc

PCNA

2,862 papers

RefSeq Summary

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synth...

Pfam Domains

PCNA_Naa 1–125UCSCProliferating cell nuclear antigen, N-terminal domain
PCNA_Caa 127–254UCSCProliferating cell nuclear antigen, C-terminal domain

Gene Aliases

HGNC Name

proliferating cell nuclear antigen

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_182649.2
p.S74Splc
c.221+5G>C
Surrounding Variants
1 paper
NM_182649.2
p.S74Splc
c.221+1G>C
2 papers
NM_182649.2
p.T73I
c.218C>T
1 paper
NM_182649.2
p.L72P
c.215T>C
1 paper
NM_182649.2
p.L72H
c.215T>A
1 paper
NM_182649.2
p.N71del1
c.211_212delGTT
4 papers
NM_182649.2
p.N71K
c.213C>G
1 paper
NM_182649.2
p.N71_L72insFs
c.213_214insT
2 papers
NM_182649.2
p.N71K
c.213C>A
1 paper
NM_182649.2
p.N71I
c.212A>T
5 papers
NM_182649.2
p.N71S
c.212A>G
1 paper
NM_182649.2
p.N71D
c.211A>G
4 papers
NM_182649.2
p.V70A
c.209T>C
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