Varaico: Literature-Extracted Genetic Variants

PDCD10

114 papers

RefSeq Summary

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated...

Pfam Domains

PDCD10_Naa 14–73UCSCProgrammed cell death protein 10, dimerisation domain

PDC10_Caa 74–161UCSCProgrammed cell death protein 10, C-terminal

Gene Aliases

HGNC Name

programmed cell death 10

HGNC Previous Symbol

CCM3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007217.4

p.Q206E

c.616C>G

Surrounding Variants

4 papers

NM_007217.4

p.L203*

c.608T>G

4 papers

NM_007217.4

p.L203*

c.608T>A

1 paper

NM_007217.4

p.A212S

c.634G>T

2 papers

NM_007217.4

p.Q200*

c.598C>T

1 paper

NM_007217.4

p.L197R

c.590T>G

6 papers

NM_007217.4

p.R196*

c.586C>T

1 paper

NM_007217.4

p.V192insFs

c.575dupT

2 papers

NM_007217.4

p.V192I

c.574G>A

1 paper

NM_007217.4

p.K186_N189delFs

c.558_567del10

1 paper

NM_007217.4

p.A187T

c.559G>A

1 paper

NM_007217.4

p.K186Splc

c.558-1G>C

1 paper

NM_007217.4

p.K186Splc

c.558-2A>C