Varaico: Literature-Extracted Genetic Variants

PDCD10

114 papers

RefSeq Summary

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated...

Pfam Domains

PDCD10_Naa 14–73UCSCProgrammed cell death protein 10, dimerisation domain

PDC10_Caa 74–161UCSCProgrammed cell death protein 10, C-terminal

Gene Aliases

HGNC Name

programmed cell death 10

HGNC Previous Symbol

CCM3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007217.4

p.A135D

c.404C>A

Surrounding Variants

1 paper

NM_007217.4

p.S136N

c.407G>A

1 paper

NM_007217.4

p.K132K

c.396G>A

2 papers

NM_007217.4

p.K132E

c.394A>G

2 papers

NM_007217.4

p.K139E

c.415A>G

3 papers

NM_007217.4

p.E140*

c.418G>T

1 paper

NM_007217.4

p.L141R

c.422T>G

1 paper

NM_007217.4

p.D143H

c.427G>C

1 paper

NM_007217.4

p.N147D

c.439A>G

1 paper

NM_007217.4

p.Y152*

c.456T>G

1 paper

NM_007217.4

p.K151_Y154del4

c.451_461del12

1 paper

NM_007217.4

p.R158_A159Splc

c.474+1G>C

5 papers

NM_007217.4

p.R158_A159Splc

c.474+1G>A