Varaico: Literature-Extracted Genetic Variants

PDCD10

114 papers

RefSeq Summary

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated...

Pfam Domains

PDCD10_Naa 14–73UCSCProgrammed cell death protein 10, dimerisation domain

PDC10_Caa 74–161UCSCProgrammed cell death protein 10, C-terminal

Gene Aliases

HGNC Name

programmed cell death 10

HGNC Previous Symbol

CCM3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007217.4

p.R126_F127delFs

c.376_380del5

Surrounding Variants

1 paper

NM_007217.4

p.R126M

c.377G>T

3 papers

NM_007217.4

p.Q129*

c.385C>T

1 paper

NM_007217.4

p.V125delFs

c.373delC

2 papers

NM_007217.4

p.R124_V125delFs

c.372_373delCT

1 paper

NM_007217.4

p.D123_Q129ins2

c.367_387dup21

1 paper

NM_007217.4

p.T130I

c.389C>T

1 paper

NM_007217.4

p.R124K

c.371G>A

1 paper

NM_007217.4

p.I131fs

c.391_392fs

1 paper

NM_007217.4

p.I131insFs

c.392_393ins37

1 paper

NM_007217.4

p.I131ins3

c.392_393ins9

1 paper

NM_007217.4

p.I131insFs

c.392_393ins31

2 papers

NM_007217.4

p.I131delFs

c.391delT