Varaico: Literature-Extracted Genetic Variants

PDCD10

114 papers

RefSeq Summary

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated...

Pfam Domains

PDCD10_Naa 14–73UCSCProgrammed cell death protein 10, dimerisation domain

PDC10_Caa 74–161UCSCProgrammed cell death protein 10, C-terminal

Gene Aliases

HGNC Name

programmed cell death 10

HGNC Previous Symbol

CCM3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_007217.4

p.K111fs

c.331_332fs

Surrounding Variants

2 papers

NM_007217.4

p.K111delFs

c.333delT

2 papers

NM_007217.4

p.Q112fs

c.334_335fs

3 papers

NM_007217.4

p.Q112_I113delFs

c.334_337del4

1 paper

NM_007217.4

p.R108L

c.323G>T

1 paper

NM_007217.4

p.S115C

c.343A>T

8 papers

NM_007217.4

p.R108*

c.322C>T

2 papers

NM_007217.4

p.K106delFs

c.317delT

2 papers

NM_007217.4

p.K106fs

c.316_317fs

3 papers

NM_007217.4

p.I117insFs

c.350_351insT

1 paper

NM_007217.4

p.E120K

c.358G>A

1 paper

NM_007217.4

p.D102A

c.305A>C

2 papers

NM_007217.4

p.R124fs

c.370_371fs