Varaico: Literature-Extracted Genetic Variants

PDCD10

114 papers

RefSeq Summary

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated...

Pfam Domains

PDCD10_Naa 14–73UCSCProgrammed cell death protein 10, dimerisation domain

PDC10_Caa 74–161UCSCProgrammed cell death protein 10, C-terminal

Gene Aliases

HGNC Name

programmed cell death 10

HGNC Previous Symbol

CCM3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007217.4

p.E52K

c.154G>A

Surrounding Variants

1 paper

NM_007217.4

p.E52Q

c.154G>C

1 paper

NM_007217.4

p.A51_E52delFs

c.151_154del4

2 papers

NM_007217.4

p.A51fs

c.151_152fs

1 paper

NM_007217.4

p.K53*

c.157A>T

2 papers

NM_007217.4

p.K50_A51Splc

c.151-1G>C

1 paper

NM_007217.4

p.K53I

c.158A>T

1 paper

NM_007217.4

p.K53R

c.158A>G

2 papers

NM_007217.4

p.E54*

c.160G>T

1 paper

NM_007217.4

p.K53insFs

c.159dupA

1 paper

NM_007217.4

p.E54fs

c.160_161fs

1 paper

NM_007217.4

p.N55fs

c.163_164fs

1 paper

NM_007217.4

p.N55delFs

c.165delA