Varaico: Literature-Extracted Genetic Variants

PDCD10

114 papers

RefSeq Summary

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated...

Pfam Domains

PDCD10_Naa 14–73UCSCProgrammed cell death protein 10, dimerisation domain

PDC10_Caa 74–161UCSCProgrammed cell death protein 10, C-terminal

Gene Aliases

HGNC Name

programmed cell death 10

HGNC Previous Symbol

CCM3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_007217.4

p.L44P

c.131T>C

Surrounding Variants

2 papers

NM_007217.4

p.L44insFs

c.131dupT

1 paper

NM_007217.4

p.R45*

c.133A>T

1 paper

NM_007217.4

p.R45fs

c.133_134fs

1 paper

NM_007217.4

p.Q42*

c.124C>T

2 papers

NM_007217.4

p.T43_A46delFs

c.129_138del10

2 papers

NM_007217.4

p.A47D

c.140C>A

1 paper

NM_007217.4

p.L38delFs

c.113delA

1 paper

NM_007217.4

p.K50Q

c.148A>C

3 papers

NM_007217.4

p.K50K

c.150G>A

1 paper

NM_007217.4

p.L38fs

c.112_113fs

1 paper

NM_007217.4

p.K50_A51Splc

c.150+1G>T

1 paper

NM_007217.4

p.K50del1

c.148_149delCTT