Varaico: Literature-Extracted Genetic Variants

PDE10A

80 papers

RefSeq Summary

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. ...

Pfam Domains

GAFaa 367–510UCSCGAF domain

GAFaa 542–688UCSCGAF domain

PDEase_Iaa 790–1021UCSC3'5'-cyclic nucleotide phosphodiesterase

Gene Aliases

HGNC Name

phosphodiesterase 10A

HGNC Alias Name

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_001130690.3

p.F334L

c.1000T>C

Surrounding Variants

1 paper

NM_001130690.3

p.F334C

c.1001T>G

2 papers

NM_001130690.3

p.F334L

c.1002T>G

2 papers

NM_001130690.3

p.F334L

c.1002T>A

1 paper

NM_001385079.1

p.L575V

c.1723T>G

1 paper

NM_001385079.1

p.D569Y

c.1705G>T

3 papers

NM_001130690.3

p.F300L

c.900C>G

3 papers

NM_001130690.3

p.F300L

c.900C>A

3 papers

NM_001130690.3

p.F300L

c.898T>C

1 paper

NM_001385079.1

p.A554A

c.1662A>C

1 paper

NM_001385079.1

p.V658_Q659del2

c.1972_1976del6

1 paper

NM_001385079.1

p.A681T

c.2041G>A

1 paper

NM_001385079.1

p.A691T

c.2071G>A