Varaico: Literature-Extracted Genetic Variants

PDE10A

80 papers

RefSeq Summary

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. ...

Pfam Domains

GAFaa 367–510UCSCGAF domain

GAFaa 542–688UCSCGAF domain

PDEase_Iaa 790–1021UCSC3'5'-cyclic nucleotide phosphodiesterase

Gene Aliases

HGNC Name

phosphodiesterase 10A

HGNC Alias Name

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001385079.1

p.A151delFs

c.452_453delCG

Surrounding Variants

1 paper

NM_001385079.1

p.G155ins1

c.463_464insCGG

1 paper

NM_001385079.1

p.G147_A148insFs

c.440_443dup4

1 paper

NM_001385079.1

p.G147V

c.440G>T

1 paper

NM_001385079.1

p.G157delFs

c.469delC

1 paper

NM_001385079.1

p.L142insFs

c.426dupC

1 paper

NM_001385079.1

p.R141H

c.422G>A

1 paper

NM_001385079.1

p.F136delFs

c.406delA

1 paper

NM_001385079.1

p.E169A

c.506A>C

1 paper

NM_001385079.1

p.P131delFs

c.392delG

1 paper

NM_001385079.1

p.T177T

c.531C>T

1 paper

NM_001385079.1

p.P123S

c.367C>T

1 paper

NM_001385079.1

p.G185S

c.553G>A