Varaico: Literature-Extracted Genetic Variants

Gene:PDE3A
Variant:p.A25T

PDE3A

166 papers

RefSeq Summary

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes ...

Pfam Domains

PDEase_Iaa 751–1020UCSC3'5'-cyclic nucleotide phosphodiesterase

Gene Aliases

HGNC Name

phosphodiesterase 3A

HGNC Alias Symbol

CGI-PDE

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000921.5
p.A25T
c.73G>A
Surrounding Variants
1 paper
NM_000921.5
p.V15I
c.43G>A
1 paper
NM_000921.5
p.P35L
c.104C>T
9 papers
NM_000921.5
p.D12N
c.34G>A
1 paper
NM_000921.5
p.R39Q
c.116G>A
1 paper
NM_000921.5
p.A8T
c.22G>A
1 paper
NM_000921.5
p.A2T
c.4G>A
1 paper
NM_000921.5
p.D49A
c.146A>C
1 paper
NM_000921.5
p.P54L
c.161C>T
1 paper
NM_000921.5
p.R59P
c.176G>C
1 paper
NM_000921.5
p.L61P
c.182T>C
1 paper
NM_000921.5
p.A64P
c.190G>C
1 paper
NM_000921.5
p.A64S
c.190G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."