Varaico: Literature-Extracted Genetic Variants

PDE4A

82 papers

RefSeq Summary

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator ...

Pfam Domains

PDE4_UCRaa 178–293UCSCPhosphodiesterase 4 upstream conserved regions (UCR)

PDEase_Iaa 432–672UCSC3'5'-cyclic nucleotide phosphodiesterase

Gene Aliases

HGNC Name

phosphodiesterase 4A

HGNC Previous Symbol

DPDE2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001111307.2

p.L14L

c.40C>T

Surrounding Variants

1 paper

NM_001111307.2

p.S13F

c.38C>T

1 paper

NM_001111307.2

p.M1V

c.1A>G

1 paper

NM_001111307.2

p.I43I

c.129C>T

1 paper

NM_001111307.2

p.R54L

c.161G>T

1 paper

NM_001111307.2

p.A55G

c.164C>G

1 paper

NM_001111307.2

p.E56D

c.168G>C

2 papers

NM_001111307.2

p.R57W

c.169C>T

1 paper

NM_001111307.2

p.A70V

c.209C>T

1 paper

NM_001111307.2

p.D72_T73insFs

c.216_217insA

1 paper

NM_001111307.2

p.H91Y

c.271C>T

1 paper

NM_001111307.2

p.S97R

c.291C>G

1 paper

NM_001111307.2

p.G101G

c.303C>A