Varaico: Literature-Extracted Genetic Variants

Gene:PDE4B

PDE4B

105 papers

RefSeq Summary

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and ...

Pfam Domains

PDE4_UCRaa 166–281UCSCPhosphodiesterase 4 upstream conserved regions (UCR)
PDEase_Iaa 405–645UCSC3'5'-cyclic nucleotide phosphodiesterase

Gene Aliases

HGNC Name

phosphodiesterase 4B

HGNC Previous Symbol

DPDE4

Papers
RefSeq ID
Protein change
DNA change
1–12 of 88 variants
4 papers
NM_002600.4
p.A112G
c.335C>G
3 papers
NM_002600.4
p.S703C
c.2107A>T
3 papers
NM_002600.4
p.S704C
c.2110A>T
2 papers
NM_002600.4
p.Q57E
c.169C>G
2 papers
NM_002600.4
p.S91I
c.272G>T
2 papers
NM_002600.4
p.Y358C
c.1073A>G
1 paper
NM_002600.4
p.M1V
c.1A>G
1 paper
NM_002600.4
p.R5K
c.14G>A
1 paper
NM_002600.4
p.T9_D14delFs
c.26_41del16
1 paper
NM_002600.4
p.V7A
c.20T>C
1 paper
NM_002600.4
p.T9M
c.26C>T
1 paper
NM_002600.4
p.D14N
c.40G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."