Varaico: Literature-Extracted Genetic Variants

Gene:PDE4B
Variant:p.M1V

PDE4B

105 papers

RefSeq Summary

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and ...

Pfam Domains

PDE4_UCRaa 166–281UCSCPhosphodiesterase 4 upstream conserved regions (UCR)
PDEase_Iaa 405–645UCSC3'5'-cyclic nucleotide phosphodiesterase

Gene Aliases

HGNC Name

phosphodiesterase 4B

HGNC Previous Symbol

DPDE4

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002600.4
p.M1V
c.1A>G
Surrounding Variants
1 paper
NM_002600.4
p.R5K
c.14G>A
1 paper
NM_002600.4
p.T9_D14delFs
c.26_41del16
1 paper
NM_002600.4
p.V7A
c.20T>C
1 paper
NM_002600.4
p.T9M
c.26C>T
1 paper
NM_002600.4
p.D14N
c.40G>A
1 paper
NM_002600.4
p.D14_N15Splc
c.42+21A>C
1 paper
NM_002600.4
p.D14_N15Splc
c.42+1777T>A
1 paper
NM_002600.4
p.V16A
c.47T>C
1 paper
NM_002600.4
p.L24*
c.71T>A
1 paper
NM_002600.4
p.K26_R41del16
c.76_122del48
1 paper
NM_002600.4
p.N33D
c.97A>G
1 paper
NM_002600.4
p.G42W
c.124G>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."