Varaico: Literature-Extracted Genetic Variants

Gene:PDE4B
Variant:p.N567D

PDE4B

105 papers

RefSeq Summary

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and ...

Pfam Domains

PDE4_UCRaa 166–281UCSCPhosphodiesterase 4 upstream conserved regions (UCR)
PDEase_Iaa 405–645UCSC3'5'-cyclic nucleotide phosphodiesterase

Gene Aliases

HGNC Name

phosphodiesterase 4B

HGNC Previous Symbol

DPDE4

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002600.4
p.N567D
c.1699A>G
Surrounding Variants
1 paper
NM_002600.4
p.N567S
c.1700A>G
1 paper
NM_002600.4
p.L565V
c.1693C>G
1 paper
NM_002600.4
p.N558fs
c.1672_1673fs
1 paper
NM_002600.4
p.R557C
c.1669C>T
1 paper
NM_002600.4
p.W578C
c.1734G>T
1 paper
NM_002600.4
p.D580E
c.1740C>A
1 paper
NM_002600.4
p.D580E
c.1740C>G
1 paper
NM_002600.4
p.I582_M583ins2
c.1746_1747ins6
1 paper
NM_002600.4
p.E593D
c.1779G>C
1 paper
NM_002600.4
p.E593D
c.1779G>T
1 paper
NM_002600.4
p.R594W
c.1780C>T
1 paper
NM_002600.4
p.V611M
c.1831G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."