phosphodiesterase 7B

3',5'-cyclic-AMP phosphodiesterase 7B

cAMP-specific phosphodiesterase 7B

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.[provided by RefSeq, Apr 2009].

Varaico: Literature-Extracted Genetic Variants

PDE7B

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name