platelet derived growth factor receptor like

PRLTS

platelet-derived growth factor receptor-like

Platelet-derived growth factor receptor-like protein

PDGF receptor beta-like tumor suppressor

PDGFR-like protein

Vascular endothelial growth factor receptor 1-like, Ig-like domain

This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

PDGFRL

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbol