Varaico: Literature-Extracted Genetic Variants

PDIA3

294 papers

RefSeq Summary

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once th...

Pfam Domains

Thioredoxinaa 26–130UCSCThioredoxin

Thioredoxin_6aa 160–355UCSCThioredoxin-like domain

Thioredoxinaa 377–482UCSCThioredoxin

Gene Aliases

HGNC Name

protein disulfide isomerase family A member 3

HGNC Previous Symbol

GRP58

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005313.5

p.L6L

c.18A>T

Surrounding Variants

1 paper

NM_005313.5

p.A7S

c.19G>T

1 paper

NM_005313.5

p.F9L

c.25T>C

1 paper

NM_005313.5

p.P10L

c.29C>T

1 paper

NM_005313.5

p.R2P

c.5G>C

1 paper

NM_005313.5

p.G11D

c.32G>A

1 paper

NM_005313.5

p.M1I

c.3G>C

1 paper

NM_005313.5

p.R2ins1

c.4_5insCCC

1 paper

NM_005313.5

p.M1I

c.3G>T

1 paper

NM_005313.5

p.G11G

c.33T>A

1 paper

NM_005313.5

p.M1T

c.2T>C

1 paper

NM_005313.5

p.M1L

c.1A>C

1 paper

NM_005313.5

p.M1L

c.1A>T