Varaico: Literature-Extracted Genetic Variants

PDIA3

294 papers

RefSeq Summary

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once th...

Pfam Domains

Thioredoxinaa 26–130UCSCThioredoxin

Thioredoxin_6aa 160–355UCSCThioredoxin-like domain

Thioredoxinaa 377–482UCSCThioredoxin

Gene Aliases

HGNC Name

protein disulfide isomerase family A member 3

HGNC Previous Symbol

GRP58

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_005313.5

p.Q481K

c.1441C>A

Surrounding Variants

1 paper

NM_005313.5

p.L480V

c.1438C>G

1 paper

NM_005313.5

p.N486N

c.1458C>T

1 paper

NM_005313.5

p.E472K

c.1414G>A

1 paper

NM_005313.5

p.R471H

c.1412G>A

1 paper

NM_005313.5

p.P495A

c.1483C>G

1 paper

NM_005313.5

p.P495L

c.1484C>T

1 paper

NM_005313.5

p.D435N

c.1303G>A

1 paper

NM_005313.5

p.M434V

c.1300A>G

1 paper

NM_005313.5

p.K433K

c.1299G>A

1 paper

NM_005313.5

p.P427A

c.1279C>G

1 paper

NM_005313.5

p.D426E

c.1278C>A

1 paper

NM_005313.5

p.D426E

c.1278C>G