PEDS1-UBE2V1 readthrough

TMEM189-UBE2V1

Kua-UEV

CROC-1B

TMEM189-UBE2V1 readthrough

Plasmanylethanolamine desaturase 1

Transmembrane protein 189

Ubiquitin-conjugating enzyme E2 variant 1

CROC-1

TRAF6-regulated IKK activator 1 beta Uev1A

UEV-1

The TMEM189-UEV mRNA is an infrequent but naturally occurring read-through transcript of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this read-through mRNA and the function of its protein product has not yet been determined. [provided by RefSeq, Oct 2010].

Varaico: Literature-Extracted Genetic Variants

PEDS1-UBE2V1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol