Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_000926.4

p.Q860K

c.2578C>A

Surrounding Variants

1 paper

NM_000926.4

p.L858F

c.2574G>T

1 paper

NM_000926.4

p.L858F

c.2574G>C

1 paper

NM_000926.4

p.L858L

c.2572T>C

1 paper

NM_000926.4

p.G857S

c.2569G>A

1 paper

NM_000926.4

p.I856T

c.2567T>C

2 papers

NM_000926.4

p.S865L

c.2594C>T

2 papers

NM_000926.4

p.S865delFs

c.2594delG

1 paper

NM_000926.4

p.K854E

c.2560A>G

1 paper

NM_000926.4

p.E851delFs

c.2551delC

2 papers

NM_000926.4

p.R869C

c.2605C>T

1 paper

NM_000926.4

p.R869H

c.2606G>A

1 paper

NM_000926.4

p.Q872*

c.2614C>T