Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.N741I

c.2222A>T

Surrounding Variants

3 papers

NM_000926.4

p.R740Q

c.2219G>A

1 paper

NM_000926.4

p.R740*

c.2218C>T

2 papers

NM_000926.4

p.I744T

c.2231T>C

1 paper

NM_000926.4

p.D746Y

c.2236G>T

2 papers

NM_000926.4

p.D746E

c.2238C>G

2 papers

NM_000926.4

p.D746E

c.2238C>A

1 paper

NM_000926.4

p.Q747H

c.2241G>T

1 paper

NM_000926.4

p.Q747H

c.2241G>C

1 paper

NM_000926.4

p.I751F

c.2251A>T

1 paper

NM_000926.4

p.G738Splc

c.2213-27C>T

1 paper

NM_000926.4

p.Q752_Y753delFs

c.2254_2257del4

1 paper

NM_000926.4

p.W755*

c.2264G>A