Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.R637*

c.1909C>T

Surrounding Variants

1 paper

NM_000926.4

p.N643I

c.1928A>T

1 paper

NM_000926.4

p.R646I

c.1937G>T

1 paper

NM_000926.4

p.V647V

c.1941T>G

1 paper

NM_000926.4

p.V648L

c.1942G>T

3 papers

NM_000926.4

p.L651V

c.1951C>G

1 paper

NM_000926.4

p.D652G

c.1955A>G

1 paper

NM_000926.4

p.A653T

c.1957G>A

1 paper

NM_000926.4

p.A653D

c.1958C>A

1 paper

NM_000926.4

p.A655V

c.1964C>T

1 paper

NM_000926.4

p.L656P

c.1967T>C

1 paper

NM_000926.4

p.P657T

c.1969C>A

1 paper

NM_000926.4

p.Q658H

c.1974G>T