Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.L545L

c.1635G>A

Surrounding Variants

1 paper

NM_000926.4

p.L545L

c.1635G>T

1 paper

NM_000926.4

p.Y544C

c.1631A>G

1 paper

NM_000926.4

p.N543Y

c.1627A>T

1 paper

NM_000926.4

p.N543D

c.1627A>G

1 paper

NM_000926.4

p.L542P

c.1625T>C

1 paper

NM_000926.4

p.Y541D

c.1621T>G

2 papers

NM_000926.4

p.P539R

c.1616C>G

1 paper

NM_000926.4

p.P539S

c.1615C>T

2 papers

NM_000926.4

p.Y538C

c.1613A>G

1 paper

NM_000926.4

p.Q536H

c.1608G>T

1 paper

NM_000926.4

p.Q536H

c.1608G>C

1 paper

NM_000926.4

p.Q536P

c.1607A>C