Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.A528A

c.1584C>G

Surrounding Variants

1 paper

NM_000926.4

p.K531Q

c.1591A>C

1 paper

NM_000926.4

p.G533C

c.1597G>T

1 paper

NM_000926.4

p.G524insFs

c.1571_1572insC

1 paper

NM_000926.4

p.L534M

c.1600C>A

1 paper

NM_000926.4

p.P521S

c.1561C>T

1 paper

NM_000926.4

p.Q536P

c.1607A>C

1 paper

NM_000926.4

p.Q536H

c.1608G>T

1 paper

NM_000926.4

p.Q536H

c.1608G>C

2 papers

NM_000926.4

p.Y538C

c.1613A>G

1 paper

NM_000926.4

p.P539S

c.1615C>T

2 papers

NM_000926.4

p.P539R

c.1616C>G

1 paper

NM_000926.4

p.L517F

c.1549C>T