Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.A505_G506del2

c.1513_1517del6

Surrounding Variants

1 paper

NM_000926.4

p.G506E

c.1517G>A

5 papers

NM_000926.4

p.A502del1

c.1504_1505delGGC

1 paper

NM_000926.4

p.A504P

c.1510G>C

1 paper

NM_000926.4

p.Y512H

c.1534T>C

1 paper

NM_000926.4

p.A503V

c.1508C>T

1 paper

NM_000926.4

p.A503D

c.1508C>A

1 paper

NM_000926.4

p.Y512insFs

c.1535dupA

1 paper

NM_000926.4

p.A502V

c.1505C>T

1 paper

NM_000926.4

p.S501ins1

c.1501_1502insGAA

1 paper

NM_000926.4

p.L515F

c.1543C>T

3 papers

NM_000926.4

p.A500insFs

c.1499_1500insA

1 paper

NM_000926.4

p.L517F

c.1549C>T