Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.L495R

c.1484T>G

Surrounding Variants

2 papers

NM_000926.4

p.G494R

c.1480G>C

2 papers

NM_000926.4

p.R492L

c.1475G>T

1 paper

NM_000926.4

p.R492Q

c.1475G>A

1 paper

NM_000926.4

p.R492W

c.1474C>T

1 paper

NM_000926.4

p.P491L

c.1472C>T

3 papers

NM_000926.4

p.A500insFs

c.1499_1500insA

1 paper

NM_000926.4

p.L490I

c.1468C>A

1 paper

NM_000926.4

p.S501ins1

c.1501_1502insGAA

1 paper

NM_000926.4

p.L489insFs

c.1465_1466insC

1 paper

NM_000926.4

p.A502V

c.1505C>T

1 paper

NM_000926.4

p.G487A

c.1460G>C

1 paper

NM_000926.4

p.A485_S486del2

c.1453_1457del6