Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.G484C

c.1450G>T

Surrounding Variants

1 paper

NM_000926.4

p.S486R

c.1456A>C

1 paper

NM_000926.4

p.K481N

c.1443G>C

1 paper

NM_000926.4

p.S486R

c.1458C>G

1 paper

NM_000926.4

p.S486R

c.1458C>A

1 paper

NM_000926.4

p.K481*

c.1441A>T

1 paper

NM_000926.4

p.K481Q

c.1441A>C

1 paper

NM_000926.4

p.G487A

c.1460G>C

1 paper

NM_000926.4

p.A485_S486del2

c.1453_1457del6

1 paper

NM_000926.4

p.C480F

c.1439G>T

1 paper

NM_000926.4

p.L489insFs

c.1465_1466insC

1 paper

NM_000926.4

p.P470_P478del0

c.1410_1433del24

1 paper

NM_000926.4

p.L490I

c.1468C>A