Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.C460C

c.1380C>T

Surrounding Variants

1 paper

NM_000926.4

p.Y463H

c.1387T>C

1 paper

NM_000926.4

p.L458M

c.1372C>A

1 paper

NM_000926.4

p.K464Q

c.1390A>C

1 paper

NM_000926.4

p.K464N

c.1392A>T

1 paper

NM_000926.4

p.K464N

c.1392A>C

3 papers

NM_000926.4

p.S454L

c.1361C>T

1 paper

NM_000926.4

p.S450Y

c.1349C>A

1 paper

NM_000926.4

p.G473V

c.1418G>T

1 paper

NM_000926.4

p.A476V

c.1427C>T

1 paper

NM_000926.4

p.A444D

c.1331C>A

2 papers

NM_000926.4

p.A444S

c.1330G>T

1 paper

NM_000926.4

p.A444T

c.1330G>A